{"id":103,"date":"2024-07-25T14:12:35","date_gmt":"2024-07-25T05:12:35","guid":{"rendered":"http:\/\/www.sanyofine.co.jp\/?page_id=103"},"modified":"2024-10-15T13:33:16","modified_gmt":"2024-10-15T04:33:16","slug":"diagnostics","status":"publish","type":"page","link":"https:\/\/www.sanyofine.co.jp\/en\/field\/diagnostics\/","title":{"rendered":"Diagnostics"},"content":{"rendered":"\r\n            <main class=\"l-main p-sub p-field p-diagnostics eng\">\r\n                <div class=\"c-bg js-parallax--sub js-animeElementpageHead isOn-\"><\/div>\r\n\r\n                <div class=\"c-topicPath\">\r\n                    <div class=\"inner\" style=\"overflow-x:hidden;\">\r\n                        <ol class=\"list\" itemscope=\"\" itemtype=\"http:\/\/schema.org\/BreadcrumbList\">\r\n                            <li itemprop=\"itemListElement\" itemscope=\"\" itemtype=\"http:\/\/schema.org\/ListItem\">\r\n                                <a href=\"\/en\/\" itemprop=\"item\"><span itemprop=\"name\">HOME<\/span><\/a>\r\n                                <meta itemprop=\"position\" content=\"1\">\r\n                            <\/li>\r\n                            <li itemprop=\"itemListElement\" itemscope=\"\" itemtype=\"http:\/\/schema.org\/ListItem\">\r\n                                <a href=\"\/en\/field\/\" itemprop=\"item\"><span itemprop=\"name\">The Business Fields<\/span><\/a>\r\n                                <meta itemprop=\"position\" content=\"2\">\r\n                            <\/li>\r\n                            <li itemprop=\"itemListElement\" itemscope=\"\" itemtype=\"http:\/\/schema.org\/ListItem\">\r\n                                <a href=\"\/en\/field\/diagnostics\/\" itemprop=\"item\"><span\r\n                                        itemprop=\"name\">Diagnostics<\/span><\/a>\r\n                                <meta itemprop=\"position\" content=\"3\">\r\n                            <\/li>\r\n                        <\/ol>\r\n                    <\/div>\r\n                <\/div>\r\n\r\n\r\n                <div class=\"c-section section-main\">\r\n                    <div class=\"inner\">\r\n                        <h1 class=\"c-title -left\">\r\n                            <span class=\"head\">Diagnostics<\/span>\r\n                        <\/h1>\r\n                    <\/div>\r\n                    <div class=\"inner \">\r\n                        <style>\r\n                            .p-sub .section-main .pic-main {\r\n                                background-image: url(\/assets\/img\/field\/diagnostics\/main.jpg);\r\n                            }\r\n\r\n                            @media screen and (max-width: 768px) {\r\n                                .p-sub .section-main .pic-main {\r\n                                    background-image: url(\/assets\/img\/field\/diagnostics\/main_sp.jpg);\r\n                                }\r\n                            }\r\n                        <\/style>\r\n                        <div class=\"pic-main pic-main2\"><\/div>\r\n                    <\/div>\r\n                    <div class=\"inner\">\r\n                        <p class=\"c-lead -left\">\r\n                            Making full use of our proprietary biotechnology we have cultivated over many years, we have discovered enzymes \r\n                            that are useful for clinical diagnosis, and developed in-vitro diagnostics such as UBASTEC-AUTO for determination \r\n                            of sulfated bile acid in urine, and ARABINITEC-AUTO for determination of D-arabinitol in blood.<br>\r\n                            These products are used for the early diagnosis of diseases at medical institutions both in Japan and overseas.\r\n                            <!-- \r\n                            We manufacture and sell in vitro diagnostic reagents for medical institutions, such as\r\n                            UBASTEC-AUTO, a urine-based diagnostic reagent for liver function (biliary atresia)\r\n                            developed with our proprietary enzymatic reaction technology.<br>\r\n                            Biliary atresia is an intractable pediatric disease that affects one out of 10,000 newborns.\r\n                            Its early detection and surgery within the first two months of life is essential for a good\r\n                            prognosis. For newborns, where it is difficult to draw blood, this product provides an\r\n                            effective testing method for the early detection.\r\n                            -->\r\n                        <\/p>\r\n                    <\/div>\r\n                <\/div>\r\n\r\n\r\n                <div class=\"c-section section-content01 c-beforeBgColor\">\r\n                    <div class=\"inner -wide\">\r\n                        <div class=\"c-tabWrap\" data-mode=\"\" id=\"target_tab_anchor1\">\r\n                            <div class=\"inner\">\r\n                                <ul class=\"c-flex -middle -center c-tab -col2 -co3-\">\r\n                                    <li>\r\n                                        <a href=\"#_js\" data-target_anchor=\"target_tab_anchor1\"\r\n                                            data-target_group=\"target_tab_group1\" data-target=\"tab_target1\"\r\n                                            class=\"tab-btn noScroll isOn\">Business and Technology<\/a>\r\n                                    <\/li>\r\n                                    <li>\r\n                                        <a href=\"#_js\" data-target_anchor=\"target_tab_anchor1\"\r\n                                            data-target_group=\"target_tab_group1\" data-target=\"tab_target2\"\r\n                                            class=\"tab-btn noScroll isOn-\">Product List<\/a>\r\n                                    <\/li>\r\n                                <\/ul>\r\n                            <\/div>\r\n\r\n                            <div class=\"c-tabTarget\" id=\"target_tab_group1\">\r\n                                <section class=\"c-tabTarget_content tab_target1 isOn\">\r\n                                    <div class=\"inner\">\r\n                                        <ul class=\"c-flex -spB c-listNav_anchor p-anchor01\">\r\n                                            <li>\r\n                                                <a href=\"#anchor1\" class=\"c-btn -arrow_bottom\">UBASTEC-AUTO<\/a>\r\n                                            <\/li>\r\n                                            <li>\r\n                                                <a href=\"#anchor2\" class=\"c-btn -arrow_bottom\">ARABINITEC-AUTO<\/a>\r\n                                            <\/li>\r\n                                        <\/ul>\r\n\r\n                                        <div class=\"c-section c-beforeBgColor-\">\r\n                                            <ul class=\"c-block c-flex c-col2 mgt0\" id=\"anchor1\">\r\n                                                <li>\r\n                                                    <h2 class=\"c-title -small -left\">\r\n                                                        <span class=\"head\">UBASTEC-AUTO <!-- For Saving Little and New Life --><\/span>\r\n                                                    <\/h2>\r\n                                                <\/li>\r\n                                                <li>\r\n                                                    <h3 class=\"c-title2\">Early Detection <!-- and Educational Activities --> of\r\n                                                        Biliary Atresia<\/h3>\r\n                                                    <p class=\"c-text\">\r\n                                                        Biliary atresia is one of intractable pediatric diseases said to\r\n                                                        occur in 1 out of 10,000 neonates. Its early detection and\r\n                                                        surgical treatment within 2 months after birth are necessary,\r\n                                                        and some methods for early detection have been tried;\r\n                                                        however, it continues to be detected occasionally after a\r\n                                                        duration of 2 months.<br>\r\n                                                        Currently, much attention has been paid to the hepatic function\r\n                                                        test with widdle as a method for early detection of biliary\r\n                                                        atresia, and enlightenment activities have been made actively.\r\n                                                        <!-- \r\n                                                        Biliary atresia, which affects 1 in 10,000 newborns, is one of\r\n                                                        the most common intractable pediatric diseases. Its detection\r\n                                                        and surgical treatment within the first two months of life are\r\n                                                        necessary for a good prognosis. Although several methods for\r\n                                                        early detection have been tried, some cases are still detected\r\n                                                        after two months. Currently, testing the liver with widdle has\r\n                                                        been paid an attention as a method for early detection of\r\n                                                        biliary atresia, and active educational efforts on it are\r\n                                                        underway.\r\n                                                        -->\r\n                                                    <\/p>\r\n                                                <\/li>\r\n                                            <\/ul>\r\n\r\n                                            <!--\r\n                                            <ul class=\"c-block c-flex c-col\">\r\n                                                <li>\r\n                                                    <h3 class=\"c-title3\">What is biliary atresia\uff1f<\/h3>\r\n                                                    <p class=\"c-text\">\r\n                                                        Biliary atresia is a disease that occurs in 1\/10,000 newborns.\r\n                                                        Its early detection and surgery within the first two months of\r\n                                                        life is important for a good prognosis. If more than two months\r\n                                                        pass without surgery, there is a high probability of developing\r\n                                                        cirrhosis.\r\n                                                    <\/p>\r\n                                                <\/li>\r\n                                            <\/ul>\r\n                                            -->\r\n\r\n                                            <ul class=\"c-block c-flex c-col\">\r\n                                                <li>\r\n                                                    <h3 class=\"c-title2\">Early Detection and Surgery within Two Months\r\n                                                        of Age<\/h3>\r\n                                                    <p class=\"c-text\">\r\n                                                        The pathway through which bile produced in the liver flows to\r\n                                                        the intestines are called the bile passage or the bile duct. If\r\n                                                        the bile passage or bile duct may become blocked at birth or\r\n                                                        shortly after birth for some reason and become unable to flow,\r\n                                                        then the bile may become stagnant in the liver and flow back\r\n                                                        into the bloodstream, causing jaundice and whitish stools. <br>If\r\n                                                        left untreated, hepatic function is gradually lost, and the\r\n                                                        liver gradually becomes hardened and cirrhotic, eventually\r\n                                                        leading to death. This disease is one of the intractable\r\n                                                        pediatric diseases and is said to occur in one out of every\r\n                                                        10,000 children. In each year, about 100 babies are affected by\r\n                                                        this disease in Japan. <br>The prognosis is often poor when the\r\n                                                        disease is not detected early in life and surgery is not\r\n                                                        performed within two months of age. Even if the surgery is\r\n                                                        performed after two months and the bile begins to flow out of\r\n                                                        the liver, the disease has already progressed to cirrhosis and\r\n                                                        thus the patient will have sequelae.\r\n                                                    <\/p>\r\n                                                <\/li>\r\n                                            <\/ul>\r\n\r\n                                            <div class=\"inner -middle\">\r\n                                                <ul class=\"c-block c-flex -center c-col\">\r\n                                                    <li><img decoding=\"async\" src=\"\/assets\/img\/field\/diagnostics\/rd2_1_graph1_en.png\"\r\n                                                            alt=\"\"><\/li>\r\n                                                <\/ul>\r\n                                                <p class=\"c-caption\">Number of registered cases of biliary atresia in\r\n                                                    Japan (from 1989 to 2020) (based on Japan Biliary Atresia Study\r\n                                                    Group and National\r\n                                                    Registry Office for Biliary Atresia, Journal of the Japan Society\r\n                                                    for Biliary Atresia, 58, 201 (2022))<\/p>\r\n                                            <\/div>\r\n\r\n                                            <!-- \r\n                                            <div class=\"c-block c-block2 c-tableWrapSp cf- js-scrollWrap\">\r\n                                                <div class=\"c-figScroll -fig1\"><img decoding=\"async\" src=\"\/assets\/img\/fig_scroll_en.png\"\r\n                                                        alt=\"\"><\/div>\r\n                                                <table class=\"c-table p-table01\">\r\n                                                    <thead>\r\n                                                        <tr>\r\n                                                            <th>1989<\/th>\r\n                                                            <th>1990<\/th>\r\n                                                            <th>1991<\/th>\r\n                                                            <th>1992<\/th>\r\n                                                            <th>1993<\/th>\r\n                                                            <th>1994<\/th>\r\n                                                            <th>1995<\/th>\r\n                                                            <th>1996<\/th>\r\n                                                            <th>1997<\/th>\r\n                                                            <th>1998<\/th>\r\n                                                            <th>1999<\/th>\r\n                                                            <th>2000<\/th>\r\n                                                            <th>2001<\/th>\r\n                                                            <th>2002<\/th>\r\n                                                            <th>2003<\/th>\r\n                                                            <th>2004<\/th>\r\n                                                        <\/tr>\r\n                                                    <\/thead>\r\n                                                    <tbody>\r\n                                                        <tr>\r\n                                                            <td>115<\/td>\r\n                                                            <td>129<\/td>\r\n                                                            <td>137<\/td>\r\n                                                            <td>127<\/td>\r\n                                                            <td>114<\/td>\r\n                                                            <td>132<\/td>\r\n                                                            <td>150<\/td>\r\n                                                            <td>130<\/td>\r\n                                                            <td>129<\/td>\r\n                                                            <td>126<\/td>\r\n                                                            <td>137<\/td>\r\n                                                            <td>126<\/td>\r\n                                                            <td>125<\/td>\r\n                                                            <td>129<\/td>\r\n                                                            <td>102<\/td>\r\n                                                            <td>114<\/td>\r\n                                                        <\/tr>\r\n                                                    <\/tbody>\r\n                                                <\/table>\r\n                                                <table class=\"c-table p-table01\">\r\n                                                    <thead>\r\n                                                        <tr>\r\n                                                            <th>2005<\/th>\r\n                                                            <th>2006<\/th>\r\n                                                            <th>2007<\/th>\r\n                                                            <th>2008<\/th>\r\n                                                            <th>2009<\/th>\r\n                                                            <th>2010<\/th>\r\n                                                            <th>2011<\/th>\r\n                                                            <th>2012<\/th>\r\n                                                            <th>2013<\/th>\r\n                                                            <th>2014<\/th>\r\n                                                            <th>2015<\/th>\r\n                                                            <th>2016<\/th>\r\n                                                            <th>2017<\/th>\r\n                                                            <th>2018<\/th>\r\n                                                            <th>2019<\/th>\r\n                                                            <th>2020<\/th>\r\n                                                        <\/tr>\r\n                                                    <\/thead>\r\n                                                    <tbody>\r\n                                                        <tr>\r\n                                                            <td>104<\/td>\r\n                                                            <td>108<\/td>\r\n                                                            <td>98<\/td>\r\n                                                            <td>108<\/td>\r\n                                                            <td>106<\/td>\r\n                                                            <td>112<\/td>\r\n                                                            <td>111<\/td>\r\n                                                            <td>109<\/td>\r\n                                                            <td>100<\/td>\r\n                                                            <td>121<\/td>\r\n                                                            <td>120<\/td>\r\n                                                            <td>87<\/td>\r\n                                                            <td>97<\/td>\r\n                                                            <td>98<\/td>\r\n                                                            <td>95<\/td>\r\n                                                            <td>100<\/td>\r\n                                                        <\/tr>\r\n                                                    <\/tbody>\r\n                                                <\/table>\r\n                                                <p class=\"c-caption\">Number of registered cases of biliary atresia in\r\n                                                    Japan (from 1989 to 2020) (based on Japan Biliary Atresia Study\r\n                                                    Group and National\r\n                                                    Registry Office for Biliary Atresia, Journal of the Japan Society\r\n                                                    for Biliary Atresia, 58, 201 (2022))<\/p>\r\n                                            <\/div>\r\n                                            -->\r\n\r\n                                            <!-- \r\n                                            <ul class=\"c-block c-block2 c-flex c-col\">\r\n                                                <li>\r\n                                                    <h3 class=\"c-title2\">Screening of Newborns with Difficulty in Blood\r\n                                                        Collection<\/h3>\r\n                                                    <p class=\"c-text\">\r\n                                                        Although it is increasingly recognized that biliary atresia has\r\n                                                        a very promising prognosis if properly operated and managed\r\n                                                        within the first two months of life, the reality is that there\r\n                                                        is no trend toward early detection of the disease. In the United\r\n                                                        Kingdom, an article published in 1995 stated that \"Despite\r\n                                                        intensive professional education in the last 15 years over 50%\r\n                                                        of children with biliary atresia are referred after 6 weeks of\r\n                                                        age,\" emphasizing the importance of early detection and the need\r\n                                                        for some kind of screening test at the same time. Previous\r\n                                                        studies have shown that urinary sulfated bile acid (USBA) is\r\n                                                        increased in case of biliary atresia, and its measuring is\r\n                                                        considered to be an effective test method for early detection of\r\n                                                        biliary atresia in newborns, for whom blood sampling is\r\n                                                        difficult.\r\n                                                    <\/p>\r\n                                                <\/li>\r\n                                            <\/ul>\r\n                                            -->\r\n\r\n                                        <\/div>\r\n                                    <\/div>\r\n\r\n                                    <div class=\"inner -wide\">\r\n                                        <div class=\"c-section c-beforeBgColor -bgBlue- pdt0\">\r\n                                            <div class=\"inner\">\r\n\r\n                                                <ul class=\"c-block c-flex c-col mgt0\">\r\n                                                    <li>\r\n                                                        <h3 class=\"c-title2\">Hepatic Function Test with Widdle<\/h3>\r\n                                                        <p class=\"c-text\">\r\n                                                            While blood samples are commonly used to test hepatic\r\n                                                            function, Sanyo Fine Co., Ltd. have developed a new method\r\n                                                            using &#8220;widdle&#8221;. This makes it possible to easily test\r\n                                                            hepatic function even in newborns, whose blood vessels are\r\n                                                            narrow and thus difficult to conduct blood samplings.\r\n                                                        <\/p>\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n\r\n                                                <!-- \r\n                                                <ul class=\"c-block c-block2 c-flex c-col2 -reverse\">\r\n                                                    <li>\r\n                                                        <h3 class=\"c-title2\">Bile Acid in Widdle<\/h3>\r\n                                                        <p class=\"c-text\">\r\n                                                            Widdle plays a role of excreting waste substances from the\r\n                                                            body. Bile acid is a substance made from cholesterol in the\r\n                                                            liver, and it helps digest and absorb ingested substances in\r\n                                                            the intestines. When the liver has become compromised, bile\r\n                                                            acid leaks into the blood, increasing the amount of bile\r\n                                                            acid in the blood. The increased bile acid in the blood has\r\n                                                            a negative effect on the body, so the increased bile acid\r\n                                                            must be excreted out of the body. As a way to do this, bile\r\n                                                            acid is converted in the liver into urinary sulfated bile\r\n                                                            acid (USBA), that can be easily excreted in widdle, and then\r\n                                                            excreted out of the body. Therefore, when the liver is\r\n                                                            compromised, the waste bile acid is excreted into the widdle\r\n                                                            in the form of USBA.\r\n                                                        <\/p>\r\n                                                    <\/li>\r\n                                                    <li>\r\n                                                        <div class=\"pic alC\"><img decoding=\"async\"\r\n                                                                src=\"\/assets\/img\/field\/diagnostics\/rd2_2_fig1_en.jpg\"\r\n                                                                alt=\"\"><\/div>\r\n                                                        <ul class=\"c-indent c-caption\">\r\n                                                            <li><span class=\"-head\">\u30fb<\/span><span class=\"-body\">Bile\r\n                                                                    acid that has been produced in the liver is stored\r\n                                                                    in the cholecyst, and it is secreted into the\r\n                                                                    intestines on food ingestion.<\/span>\r\n                                                            <\/li>\r\n                                                            <li><span class=\"-head\">\u30fb<\/span><span class=\"-body\">Bile\r\n                                                                    acid that has been absorbed in the intestines is\r\n                                                                    returned to the liver through the portal\r\n                                                                    vein.<\/span><\/li>\r\n                                                        <\/ul>\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n                                                -->\r\n\r\n                                                <!-- \r\n                                                <ul class=\"c-block c-block2  c-flex c-col\">\r\n                                                    <li>\r\n                                                        <h3 class=\"c-title2\">Assay of Urinary Sulfated Bile Acid (USBA)\r\n                                                        <\/h3>\r\n                                                        <p class=\"c-text\">\r\n                                                            For the assay of urinary sulfated bile acid (USBA),\r\n                                                            sulfate-conjugated bile acid must first be converted back to\r\n                                                            bile acid. Until now, there was no easy way to do this,\r\n                                                            therefor it had never been applied to in vitro diagnostics.\r\n                                                            Sanyo Fine Co., Ltd. has conducted research on enzymes that\r\n                                                            can easily convert the sulfate-conjugated bile acids back to\r\n                                                            bile acids, and discovered a new enzyme, bile acid sulfate\r\n                                                            sulfatase. By using this enzyme, it is now possible to assay\r\n                                                            sulfate-conjugated bile acid, which has been difficult with\r\n                                                            conventional methods and thus has not been put to practical\r\n                                                            use.\r\n                                                        <\/p>\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n                                                -->\r\n\r\n                                                <ul class=\"c-block c-block2  c-flex c-col2--half c-imageFit\">\r\n                                                    <li>\r\n                                                        <div class=\"pic\"><img decoding=\"async\"\r\n                                                                src=\"\/assets\/img\/field\/diagnostics\/rd2_2_ph1.jpg\"\r\n                                                                alt=\"\"><\/div>\r\n                                                        <p class=\"c-caption\">Automatic analyzer for laboratory\r\n                                                            examination<\/p>\r\n                                                    <\/li>\r\n                                                    <li>\r\n                                                        <div class=\"pic\"><img decoding=\"async\"\r\n                                                                src=\"\/assets\/img\/field\/diagnostics\/rd2_2_ph2.jpg\"\r\n                                                                alt=\"\"><\/div>\r\n                                                        <p class=\"c-caption\">UBASTEC-AUTO,For the assay of urinary bile\r\n                                                            acid sulfates\r\n                                                        <\/p>\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n\r\n                                                <ul class=\"c-block c-flex\">\r\n                                                    <li>\r\n                                                        <h3 class=\"c-title2\">Enlightenment Activities<\/h3>\r\n                                                        <p class=\"c-text\">\r\n                                                            The Association for Saving Children with Biliary Atresia, a\r\n                                                            family group of patients with biliary atresia, holds a forum on\r\n                                                            pediatric intractable diseases as an enlightenment activity on\r\n                                                            the importance of early detection and improvement of therapeutic\r\n                                                            methods to overcome biliary atresia.<br>Through the implementation\r\n                                                            of this forum, they are actively lobbying Japanese government\r\n                                                            and other related organizations to introduce USBA testing in\r\n                                                            infant health checkups.\r\n                                                        <\/p>\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n\r\n                                               <ul class=\"c-block c-block2 c-flex c-col2 -reverse\">\r\n                                                    <li>\r\n                                                        <h3 class=\"c-title5\">The 7th forum: December 21, 2019<\/h3>\r\n                                                        <!-- <p class=\"c-text\"><\/p> -->\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n\r\n                                                <table class=\"c-table c-table2\">\r\n                                                    <tr>\r\n                                                        <th>Venue<\/th>\r\n                                                        <td>Sendai International Center (Sendai, Miyagi, Japan)\r\n                                                        <\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Theme<\/th>\r\n                                                        <td>Proposals for Early Detection and Diagnosis of Biliary\r\n                                                            Atresia Contents<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Contents<\/th>\r\n                                                        <td>\r\n                                                            <ul class=\"c-indent\">\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff081\uff09<\/span>\r\n                                                                    <span class=\"-body\">Greetings by guest Ms. Miyuki\r\n                                                                        Yusa (Member of Miyagi Prefectural\r\n                                                                        Assembly)<\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff082\uff09<\/span>\r\n                                                                    <span class=\"-body\">Greetings from the organizer<br>\r\n                                                                        Dr. Yuichiro Yamashiro (Chairperson, the\r\n                                                                        Workshop for Early Detection of Biliary\r\n                                                                        Atresia)<br>\r\n                                                                        Mr. Koichi Takeuchi (Representative, The\r\n                                                                        Association for Saving Children with Biliary\r\n                                                                        Atresia)<\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff083\uff09<\/span>\r\n                                                                    <span class=\"-body\">Thoughts as a parent<br>\r\n                                                                        Ms. Kyoko Otomo (Patient Family Member, Miyagi\r\n                                                                        Branch of the Association for Saving Children\r\n                                                                        with Biliary Atresia)<\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff084\uff09<\/span>\r\n                                                                    <span class=\"-body\">\r\n                                                                        Early detection forum\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">1. <\/span>\r\n                                                                                <span class=\"-body\">Current status and\r\n                                                                                    issues in the treatment of biliary\r\n                                                                                    atresia<br>\r\n                                                                                    Dr. Masaki Nio (Professor,\r\n                                                                                    Department of Pediatric Surgery,\r\n                                                                                    Graduate School of Medicine, Tohoku\r\n                                                                                    Univ.)<\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">2. <\/span>\r\n                                                                                <span class=\"-body\">\r\n                                                                                    Implementation of mass screening\r\n                                                                                    <ul class=\"c-indent\">\r\n                                                                                        <li><span\r\n                                                                                                class=\"-head\">\u30fb<\/span><span\r\n                                                                                                class=\"-body\">In case of\r\n                                                                                                Nagasaki Pref.: Dr.\r\n                                                                                                Masayuki Obatake\r\n                                                                                                (Specially Appointed\r\n                                                                                                Professor, Department of\r\n                                                                                                Surgery, Kochi Medical\r\n                                                                                                School, Kochi\r\n                                                                                                Univ.)<\/span>\r\n                                                                                        <\/li>\r\n                                                                                        <li><span\r\n                                                                                                class=\"-head\">\u30fb<\/span><span\r\n                                                                                                class=\"-body\">In case of\r\n                                                                                                Okinawa Pref.: Dr. Ken\r\n                                                                                                Suzuki (Faculty of\r\n                                                                                                Pharmacy and\r\n                                                                                                Pharmaceutical Sciences,\r\n                                                                                                Josai University;\r\n                                                                                                Auditor, Japanese\r\n                                                                                                Society for Neonatal\r\n                                                                                                Screening)<\/span>\r\n                                                                                        <\/li>\r\n                                                                                    <\/ul>\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">3. <\/span>\r\n                                                                                <span class=\"-body\">Current status and\r\n                                                                                    proposals in Miyagi Pref.<br>\r\n                                                                                    Dr. Hiromu Tanaka (Director,\r\n                                                                                    Department of Surgery, Miyagi\r\n                                                                                    Children&#8217;s Hospital)<\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                            <\/ul>\r\n                                                        <\/td>\r\n                                                    <\/tr>\r\n                                                <\/table>\r\n\r\n                                            <\/div>\r\n                                        <\/div>\r\n                                    <\/div>\r\n\r\n\r\n                                    <div class=\"c-section c-beforeBgColor -bgBlue\">\r\n                                        <div class=\"inner\">\r\n                                            <ul class=\"c-block c-flex c-col2 mgt0\" id=\"anchor2\">\r\n                                                <li>\r\n                                                    <h2 class=\"c-title -small -left\">\r\n                                                        <span class=\"head\">ARABINITEC-AUTO<\/span>\r\n                                                    <\/h2>\r\n                                                <\/li>\r\n                                                <li>\r\n                                                    <h3 class=\"c-title2\">Determination of D-Arabinitol in Serum<\/h3>\r\n                                                    <p class=\"c-text\">\r\n                                                        D-arabinitol is the characteristic a metabolite produced by\r\n                                                        genus Candida which is well known to cause a deepseated\r\n                                                        mycosis in mammals. The serum level of D-arabinitol is\r\n                                                        known to increase when Candida yeast proliferates in the\r\n                                                        body of a patient having an invasive candidiasis. Thus\r\n                                                        determination of serum level of D-arabinitol could be a good\r\n                                                        marker for the attenuation of a Candida species in a body.<br>\r\n                                                        ARABINITEC-AUTO is a simple assay reagent kit for the\r\n                                                        automatic measurement of D-arabinitol in serum. This kit\r\n                                                        utilizes an enzyme system which comprises D-arabinitol\r\n                                                        dehydrogenase combined with a color development system\r\n                                                        of diaphorase with WST-1, and enables a rapid and highly\r\n                                                        sensitive determination of D-arabinitol in a single channel\r\n                                                        using a self blank method without pretreatment.\r\n                                                    <\/p>\r\n                                                <\/li>\r\n                                            <\/ul>\r\n\r\n                                            <!-- \r\n                                            <ul class=\"c-block c-block2 c-flex c-col2 -reverse\">\r\n                                                <li>\r\n                                                    <h3 class=\"c-title2\">Past Forums<\/h3>\r\n                                                    <p class=\"c-text\">Sanyo Fine Co., Ltd. actively supports the Forum.\r\n                                                    <\/p>\r\n                                                <\/li>\r\n                                            <\/ul>\r\n\r\n                                            <div class=\"p-itemWrap\">\r\n                                                <h3 class=\"c-title5\">The 7th forum\uff1aDecember 21, 2019<\/h3>\r\n                                                <table class=\"c-table c-table2\">\r\n                                                    <tr>\r\n                                                        <th>Venue<\/th>\r\n                                                        <td>Sendai International Center (Sendai, Miyagi, Japan)\r\n                                                        <\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Theme<\/th>\r\n                                                        <td>Proposals for Early Detection and Diagnosis of Biliary\r\n                                                            Atresia Contents<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Contents<\/th>\r\n                                                        <td>\r\n                                                            <ul class=\"c-indent\">\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff081\uff09<\/span>\r\n                                                                    <span class=\"-body\">Greetings by guest Ms. Miyuki\r\n                                                                        Yusa (Member of Miyagi Prefectural\r\n                                                                        Assembly)<\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff082\uff09<\/span>\r\n                                                                    <span class=\"-body\">Greetings from the organizer<br>\r\n                                                                        Dr. Yuichiro Yamashiro (Chairperson, the\r\n                                                                        Workshop for Early Detection of Biliary\r\n                                                                        Atresia)<br>\r\n                                                                        Mr. Koichi Takeuchi (Representative, The\r\n                                                                        Association for Saving Children with Biliary\r\n                                                                        Atresia)<\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff083\uff09<\/span>\r\n                                                                    <span class=\"-body\">Thoughts as a parent<br>\r\n                                                                        Ms. Kyoko Otomo (Patient Family Member, Miyagi\r\n                                                                        Branch of the Association for Saving Children\r\n                                                                        with Biliary Atresia)<\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff084\uff09<\/span>\r\n                                                                    <span class=\"-body\">\r\n                                                                        Early detection forum\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">1. <\/span>\r\n                                                                                <span class=\"-body\">Current status and\r\n                                                                                    issues in the treatment of biliary\r\n                                                                                    atresia<br>\r\n                                                                                    Dr. Masaki Nio (Professor,\r\n                                                                                    Department of Pediatric Surgery,\r\n                                                                                    Graduate School of Medicine, Tohoku\r\n                                                                                    Univ.)<\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">2. <\/span>\r\n                                                                                <span class=\"-body\">\r\n                                                                                    Implementation of mass screening\r\n                                                                                    <ul class=\"c-indent\">\r\n                                                                                        <li><span\r\n                                                                                                class=\"-head\">\u30fb<\/span><span\r\n                                                                                                class=\"-body\">In case of\r\n                                                                                                Nagasaki Pref.: Dr.\r\n                                                                                                Masayuki Obatake\r\n                                                                                                (Specially Appointed\r\n                                                                                                Professor, Department of\r\n                                                                                                Surgery, Kochi Medical\r\n                                                                                                School, Kochi\r\n                                                                                                Univ.)<\/span>\r\n                                                                                        <\/li>\r\n                                                                                        <li><span\r\n                                                                                                class=\"-head\">\u30fb<\/span><span\r\n                                                                                                class=\"-body\">In case of\r\n                                                                                                Okinawa Pref.: Dr. Ken\r\n                                                                                                Suzuki (Faculty of\r\n                                                                                                Pharmacy and\r\n                                                                                                Pharmaceutical Sciences,\r\n                                                                                                Josai University;\r\n                                                                                                Auditor, Japanese\r\n                                                                                                Society for Neonatal\r\n                                                                                                Screening)<\/span>\r\n                                                                                        <\/li>\r\n                                                                                    <\/ul>\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">3. <\/span>\r\n                                                                                <span class=\"-body\">Current status and\r\n                                                                                    proposals in Miyagi Pref.<br>\r\n                                                                                    Dr. Hiromu Tanaka (Director,\r\n                                                                                    Department of Surgery, Miyagi\r\n                                                                                    Children's Hospital)<\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                            <\/ul>\r\n                                                        <\/td>\r\n                                                    <\/tr>\r\n                                                <\/table>\r\n                                            <\/div>\r\n\r\n\r\n                                            <div class=\"p-itemWrap\">\r\n                                                <h3 class=\"c-title5\">The 6th forum\uff1aFebruary 19, 2011<\/h3>\r\n                                                <table class=\"c-table c-table2\">\r\n                                                    <tr>\r\n                                                        <th>Venue<\/th>\r\n                                                        <td>Miyagi Prefectural Medical Association Hall (Sendai, Miyagi,\r\n                                                            Japan)<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Theme<\/th>\r\n                                                        <td>Theme Proposals for Early Detection and Diagnosis of Biliary\r\n                                                            Atresia Contents<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Contents<\/th>\r\n                                                        <td>\r\n                                                            <ul class=\"c-indent\">\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff081\uff09<\/span>\r\n                                                                    <span class=\"-body\">Greetings from the organizer Dr.\r\n                                                                        Kimio Nakagawa (Chairperson, the Miyagi\r\n                                                                        Association of Obstetricians and\r\n                                                                        Gynecologists)Dr. Yuichiro Yamashiro\r\n                                                                        (Chairperson, the Workshop for Early Detection\r\n                                                                        of Biliary Atresia) <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff082\uff09<\/span>\r\n                                                                    <span class=\"-body\">Thoughts as a parent Ms. Kyoko\r\n                                                                        Otomo (Patient Family Member, Miyagi Branch of\r\n                                                                        the Association for Saving Children with Biliary\r\n                                                                        Atresia) <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff083\uff09<\/span>\r\n                                                                    <span class=\"-body\">\r\n                                                                        Forum\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">1. <\/span>\r\n                                                                                <span class=\"-body\">Necessity and Future\r\n                                                                                    Prospects of Mass Screening for\r\n                                                                                    Biliary Atresia<br>\r\n                                                                                    Dr. Kimio Nakagawa (Chairperson, the\r\n                                                                                    Miyagi Association of Obstetricians\r\n                                                                                    and Gynecologists)<br>\r\n                                                                                    Dr. Yuichiro Yamashiro (Chairperson,\r\n                                                                                    the Workshop for Early Detection of\r\n                                                                                    Biliary Atresia) <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">2. <\/span>\r\n                                                                                <span class=\"-body\">\r\n                                                                                    Implementation of mass screening -\r\n                                                                                    In case of Nagasaki Pref\r\n                                                                                    <ul class=\"c-indent\">\r\n                                                                                        <li><span\r\n                                                                                                class=\"-head\">\u30fb<\/span><span\r\n                                                                                                class=\"-body\">In case of\r\n                                                                                                Nagasaki Pref.: Dr.\r\n                                                                                                Masayuki Obatake\r\n                                                                                                (Lecturer, Department of\r\n                                                                                                Surgical Oncology,\r\n                                                                                                Graduate School of\r\n                                                                                                Biomedical Sciences,\r\n                                                                                                Nagasaki Univ.)<\/span>\r\n                                                                                        <\/li>\r\n                                                                                        <li><span\r\n                                                                                                class=\"-head\">\u30fb<\/span><span\r\n                                                                                                class=\"-body\">In case of\r\n                                                                                                Okinawa Pref.: Dr. Ryo\r\n                                                                                                Kinjo (Deputy Department\r\n                                                                                                Director, Department of\r\n                                                                                                Pediatric Surgery,\r\n                                                                                                Okinawa Prefectural\r\n                                                                                                Nanbu Medical Center and\r\n                                                                                                Children's Medical\r\n                                                                                                Center)<\/span>\r\n                                                                                        <\/li>\r\n                                                                                    <\/ul>\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">3. <\/span>\r\n                                                                                <span class=\"-body\">Current Status and\r\n                                                                                    Proposals in Miyagi Prefecture\r\n                                                                                    <br>Dr. Masaki Nio (Professor,\r\n                                                                                    Department of Pediatric Surgery,\r\n                                                                                    Graduate School of Medicine, Tohoku\r\n                                                                                    Univ.)<\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                            <\/ul>\r\n                                                        <\/td>\r\n                                                    <\/tr>\r\n                                                <\/table>\r\n                                            <\/div>\r\n\r\n\r\n                                            <div class=\"p-itemWrap\">\r\n                                                <h3 class=\"c-title5\">The 5th forum\uff1aSeptember 8, 2007<\/h3>\r\n                                                <table class=\"c-table c-table2\">\r\n                                                    <tr>\r\n                                                        <th>Venue<\/th>\r\n                                                        <td>Garden Restaurant Tokugawaen (Nagoya, Aichi, Japan)<\/td>\r\n                                                    <\/tr>\r\n\r\n                                                    <tr>\r\n                                                        <th>Theme<\/th>\r\n                                                        <td>Proposals for Early Detection and Diagnosis of Biliary\r\n                                                            Atresia<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Contents<\/th>\r\n                                                        <td>\r\n                                                            <ul class=\"c-indent\">\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(1)<\/span>\r\n                                                                    <span class=\"-body\">Greetings from the organizer<br>\r\n                                                                        Dr. Yuichiro Yamashiro (Chairperson, the\r\n                                                                        Workshop for Early Detection of Biliary Atresia;\r\n                                                                        Specially Appointed Professor, Juntendo Univ.)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(2)<\/span>\r\n                                                                    <span class=\"-body\">Opening remarks<br>\r\n                                                                        Dr. Takashi Hashimoto (Professor, Department of\r\n                                                                        Pediatric Surgery, Fujita Health Univ.)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(3)<\/span>\r\n                                                                    <span class=\"-body\">Thoughts as a parent<br>\r\n                                                                        Mr. Yoshiro Hase (Patient Family Member, Aichi\r\n                                                                        Branch of the Association for Saving Children\r\n                                                                        with Biliary Atresia)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(4)<\/span>\r\n                                                                    <span class=\"-body\">Early detection forum<br>\r\n                                                                        Chairperson: Dr. Takao Sekiya (Lecturer,\r\n                                                                        Department of Obstetrics and Gynecology, Fujita\r\n                                                                        Health Univ.)\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">1.<\/span>\r\n                                                                                <span class=\"-body\">Current status of\r\n                                                                                    diagnosis and treatment of biliary\r\n                                                                                    atresia<br>\r\n                                                                                    Dr. Masaki Nio (Director, Department\r\n                                                                                    of Surgery, Miyagi Children's\r\n                                                                                    Hospital)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">2.<\/span>\r\n                                                                                <span class=\"-body\">Early detection of\r\n                                                                                    biliary atresia in Nagasaki Pref.:\r\n                                                                                    Last year's efforts and future\r\n                                                                                    issues<br>\r\n                                                                                    Dr. Masayuki Obatake (Lecturer,\r\n                                                                                    Department of Surgical Oncology,\r\n                                                                                    Graduate School of Biomedical\r\n                                                                                    Sciences, Nagasaki Univ.)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">3.<\/span>\r\n                                                                                <span class=\"-body\">Pilot study on\r\n                                                                                    biliary atresia by USBA assay<br>\r\n                                                                                    Dr. Mitsuyoshi Suzuki (Assistant\r\n                                                                                    Professor, Department of Pediatrics\r\n                                                                                    and Adolescent Medicine, Juntendo\r\n                                                                                    Univ.)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                            <\/ul>\r\n                                                        <\/td>\r\n\r\n                                                    <\/tr>\r\n                                                <\/table>\r\n                                            <\/div>\r\n\r\n\r\n\r\n                                            <div class=\"p-itemWrap\">\r\n                                                <h3 class=\"c-title5\">The 4th forum\uff1aJuly 15, 2006<\/h3>\r\n                                                <table class=\"c-table c-table2\">\r\n                                                    <tr>\r\n                                                        <th>Venue<\/th>\r\n                                                        <td>Lasse Hall (Kobe, Hyogo, Japan)<\/td>\r\n                                                    <\/tr>\r\n\r\n                                                    <tr>\r\n                                                        <th>Theme<\/th>\r\n                                                        <td>Proposals for Early Detection and Diagnosis of Biliary\r\n                                                            Atresia - Aiming for Detection within One Month of Age<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Contents<\/th>\r\n                                                        <td>\r\n                                                            <ul class=\"c-indent\">\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(1)<\/span>\r\n                                                                    <span class=\"-body\">Greetings from the organizer<br>\r\n                                                                        Dr. Yuichiro Yamashiro (Chairperson, the\r\n                                                                        Workshop for Early Detection of Biliary Atresia;\r\n                                                                        Professor, Juntendo Univ.)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(2)<\/span>\r\n                                                                    <span class=\"-body\">Greetings by guests<br>\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li><span class=\"-head\">\u30fb<\/span><span\r\n                                                                                    class=\"-body\">Promotion of medical\r\n                                                                                    and welfare\r\n                                                                                    administration<br>\r\n                                                                                    Mr. Toshizo Ido (Governor, Hyogo\r\n                                                                                    Pref.)<\/span>\r\n                                                                            <\/li>\r\n                                                                            <li><span class=\"-head\">\u30fb<\/span><span\r\n                                                                                    class=\"-body\">Current status of\r\n                                                                                    pediatric intractable\r\n                                                                                    diseases<br>\r\n                                                                                    Dr. Hajime Nakamura (Director, Hyogo\r\n                                                                                    Prefectural\r\n                                                                                    Kobe Children's Hospital)<\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(3)<\/span>\r\n                                                                    <span class=\"-body\">Keynote lecture<br>\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li><span class=\"-head\">\u30fb<\/span><span\r\n                                                                                    class=\"-body\">Early detection and\r\n                                                                                    diagnosis are the lifeline\r\n                                                                                    for children with biliary\r\n                                                                                    atresia<br>\r\n                                                                                    Mr. Yujiro Maru (Special Officer,\r\n                                                                                    the\r\n                                                                                    Association for Saving Children with\r\n                                                                                    Biliary\r\n                                                                                    Atresia)<\/span>\r\n                                                                            <\/li>\r\n                                                                            <li><span class=\"-head\">\u30fb<\/span><span\r\n                                                                                    class=\"-body\">Thoughts as a\r\n                                                                                    parent<br>\r\n                                                                                    Ms. Yoko Hiranuma (Parent of biliary\r\n                                                                                    atresia\r\n                                                                                    patient)<\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(4)<\/span>\r\n                                                                    <span class=\"-body\">Early detection forum<br>\r\n                                                                        Chairperson: Dr. Takao Sekiya (Lecturer,\r\n                                                                        Department of Obstetrics and Gynecology, Fujita\r\n                                                                        Health Univ.)\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">1.<\/span>\r\n                                                                                <span class=\"-body\">Timing of diagnosis\r\n                                                                                    and outcome of treatment in Japan:\r\n                                                                                    From the data registered by Japanese\r\n                                                                                    Biliary Atresia Society<br>\r\n                                                                                    Dr. Masaki Nio (Director, Department\r\n                                                                                    of Surgery, Miyagi Children's\r\n                                                                                    Hospital)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">2.<\/span>\r\n                                                                                <span class=\"-body\">Obstetrician's\r\n                                                                                    approach for early detection of\r\n                                                                                    biliary atresia<br>\r\n                                                                                    Dr. Hideaki Masuzaki (Associate\r\n                                                                                    Professor, Department of Obstetrics\r\n                                                                                    and Gynecology, School of Medicine,\r\n                                                                                    Nagasaki Univ.)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">3.<\/span>\r\n                                                                                <span class=\"-body\">Early detection of\r\n                                                                                    biliary atresia - USBA assay<br>\r\n                                                                                    Dr. Toshihiro Muraji (Director,\r\n                                                                                    Department of Pediatric Surgery,\r\n                                                                                    Hyogo Prefectural Kobe Children's\r\n                                                                                    Hospital)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                            <\/ul>\r\n                                                        <\/td>\r\n\r\n                                                    <\/tr>\r\n                                                <\/table>\r\n                                            <\/div>\r\n\r\n\r\n\r\n                                            <div class=\"p-itemWrap\">\r\n                                                <h3 class=\"c-title5\">The 3th forum\uff1aWednesday, November 23, 2005<\/h3>\r\n                                                <table class=\"c-table c-table2\">\r\n                                                    <tr>\r\n                                                        <th>Venue<\/th>\r\n                                                        <td>Nagasaki Prefectural Medical Association Hall (Nagasaki,\r\n                                                            Japan)<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Theme<\/th>\r\n                                                        <td>Reality of Overlooked Pediatric Intractable Disease -\r\n                                                            Proposals for Early Detection and Diagnosis of Biliary\r\n                                                            Atresia<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Contents<\/th>\r\n                                                        <td>\r\n                                                            <ul class=\"c-indent\">\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(1)<\/span>\r\n                                                                    <span class=\"-body\">Greetings<br>\r\n                                                                        Mr. Shinichiro Yamazaki (Director, Welfare and\r\n                                                                        Public Health Department, Nagasaki Pref.)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(2)<\/span>\r\n                                                                    <span class=\"-body\">Story of experience<br>\r\n                                                                        Early detection and diagnosis are the lifeline\r\n                                                                        for children with biliary atresia<br>\r\n                                                                        Ms. Mayumi Yakui (Director, Nagasaki Branch of\r\n                                                                        the Association for Saving Children with Biliary\r\n                                                                        Atresia)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(3)<\/span>\r\n                                                                    <span class=\"-body\">Lectures<br>\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">1.<\/span>\r\n                                                                                <span class=\"-body\">Biliary atresia:\r\n                                                                                    Biliary stasis in neonates and\r\n                                                                                    infants and its early detection<br>\r\n                                                                                    Dr. Toshihiro Muraji (Director,\r\n                                                                                    Department of Pediatric Surgery,\r\n                                                                                    Hyogo Prefectural Kobe Children's\r\n                                                                                    Hospital)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">2.<\/span>\r\n                                                                                <span class=\"-body\">Case study on a\r\n                                                                                    patient with Kasai operation in the\r\n                                                                                    neonatal period - Proposal for early\r\n                                                                                    diagnosis<br>\r\n                                                                                    Dr. Iwao Yamagai (Associate\r\n                                                                                    Professor, Department of Physiology,\r\n                                                                                    Faculty of Medicine, Yamagata Univ.)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">3.<\/span>\r\n                                                                                <span class=\"-body\">Early detection of\r\n                                                                                    biliary atresia - with USBA assay\r\n                                                                                    and stool color card<br>\r\n                                                                                    Dr. Masayuki Obatake (Lecturer,\r\n                                                                                    Department of Surgical Oncology,\r\n                                                                                    Graduate School of Biomedical\r\n                                                                                    Sciences, Nagasaki Univ.)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">4.<\/span>\r\n                                                                                <span class=\"-body\">International trends\r\n                                                                                    of standardization in the field of\r\n                                                                                    general laboratory tests such as\r\n                                                                                    urine and stool<br>\r\n                                                                                    Dr. Kiichi Ito (Professor,\r\n                                                                                    Department of Basic Human Sciences,\r\n                                                                                    Kanagawa Univ. of Human Services;\r\n                                                                                    Chairman, Committee for\r\n                                                                                    Standardization of Urinalysis,\r\n                                                                                    Japanese Committee for Clinical\r\n                                                                                    Laboratory Standards [JCCLS])\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">5.<\/span>\r\n                                                                                <span class=\"-body\">Toward early\r\n                                                                                    detection and diagnosis of biliary\r\n                                                                                    atresia - Hoping for early use of\r\n                                                                                    the USBA method<br>\r\n                                                                                    The Association for Saving Children\r\n                                                                                    with Biliary Atresia\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                            <\/ul>\r\n                                                        <\/td>\r\n\r\n                                                    <\/tr>\r\n                                                <\/table>\r\n                                            <\/div>\r\n\r\n\r\n                                            <div class=\"p-itemWrap\">\r\n                                                <h3 class=\"c-title5\">The 2th forum\uff1aSaturday, October 9, 2004<\/h3>\r\n                                                <table class=\"c-table c-table2\">\r\n                                                    <tr>\r\n                                                        <th>Venue<\/th>\r\n                                                        <td>Sendai Silver Center (Sendai, Miyagi, Japan)<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Theme<\/th>\r\n                                                        <td>Overcoming Biliary Atresia: Proposals for Early Diagnosis\r\n                                                            and New Treatment Strategies<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Contents<\/th>\r\n                                                        <td>\r\n                                                            <ul class=\"c-indent\">\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(1)<\/span>\r\n                                                                    <span class=\"-body\">Greetings<br>\r\n                                                                        Mr. Shiro Asano (Governor, Miyagi Pref.)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(2)<\/span>\r\n                                                                    <span class=\"-body\">Opening remarks<br>\r\n                                                                        Mr. Futoshi Utsumi (Member of Miyagi Prefectural\r\n                                                                        Assembly)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(3)<\/span>\r\n                                                                    <span class=\"-body\">Keynote Lecture<br>\r\n                                                                        Issues in Pediatric Medical Care and Children's\r\n                                                                        Hospital<br>\r\n                                                                        Dr. Ryoji Ohi (Director, Miyagi Children's\r\n                                                                        Hospital)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(4)<\/span>\r\n                                                                    <span class=\"-body\">Lectures<br>\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">1.<\/span>\r\n                                                                                <span class=\"-body\">Biliary stasis in\r\n                                                                                    neonates and infants<br>\r\n                                                                                    Dr. Daiki Abukawa (Director,\r\n                                                                                    Department of General Medicine,\r\n                                                                                    Miyagi Children's Hospital)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">2.<\/span>\r\n                                                                                <span class=\"-body\">Surgical treatment\r\n                                                                                    of biliary atresia<br>\r\n                                                                                    Dr. Masaki Nio (Director, Department\r\n                                                                                    of Surgery, Miyagi Children's\r\n                                                                                    Hospital)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">3.<\/span>\r\n                                                                                <span class=\"-body\">Current status of\r\n                                                                                    liver transplantation<br>\r\n                                                                                    Dr. Susumu Satomi (Professor,\r\n                                                                                    Department of Advanced Surgery,\r\n                                                                                    School of Medicine, Tohoku Univ.)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">4.<\/span>\r\n                                                                                <span class=\"-body\">Feasibility of mass\r\n                                                                                    screening for biliary atresia by\r\n                                                                                    assay of urinary sulfated bile\r\n                                                                                    acid<br>\r\n                                                                                    Dr. Toshihiro Muraji (Director,\r\n                                                                                    Department of Pediatric Surgery,\r\n                                                                                    Hyogo Prefectural Kobe Children's\r\n                                                                                    Hospital)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">5.<\/span>\r\n                                                                                <span class=\"-body\">Current status and\r\n                                                                                    issues of patients with biliary\r\n                                                                                    atresia<br>\r\n                                                                                    Mr. Yujiro Ishimaru (Representative,\r\n                                                                                    The Association for Saving Children\r\n                                                                                    with Biliary Atresia)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                            <\/ul>\r\n                                                        <\/td>\r\n\r\n                                                    <\/tr>\r\n                                                <\/table>\r\n                                            <\/div>\r\n\r\n\r\n\r\n                                            <div class=\"p-itemWrap\">\r\n                                                <h3 class=\"c-title5\">The 1th forum\uff1a Saturday, February 28, 2004<\/h3>\r\n                                                <table class=\"c-table c-table2\">\r\n                                                    <tr>\r\n                                                        <th>Venue<\/th>\r\n                                                        <td>Osaka Dawn Center (Osaka Prefectural Women's Center) (Osaka,\r\n                                                            Japan)<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Theme<\/th>\r\n                                                        <td>Biliary Atresia: Development of Early Detection Methods and\r\n                                                            the Forefront of Treatment<\/td>\r\n                                                    <\/tr>\r\n                                                    <tr>\r\n                                                        <th>Contents<\/th>\r\n                                                        <td>\r\n                                                            <ul class=\"c-indent\">\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">(1)<\/span>\r\n                                                                    <span class=\"-body\">Keynote Lecture<br>\r\n                                                                        Current status and issues of patients with\r\n                                                                        biliary atresia<br>\r\n                                                                        Mr. Yujiro Ishimaru (Representative, The\r\n                                                                        Association for Saving Children with Biliary\r\n                                                                        Atresia)\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                                <li>\r\n                                                                    <span class=\"-head\">\uff082\uff09<\/span>\r\n                                                                    <span class=\"-body\">Lectures<br>\r\n                                                                        <ul class=\"c-indent\">\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">1.<\/span>\r\n                                                                                <span class=\"-body\">Progress in\r\n                                                                                    diagnosis and treatment: Development\r\n                                                                                    and future development of USBA assay\r\n                                                                                    for early detection<br>\r\n                                                                                    Dr. Toshihiro Muraji (Director,\r\n                                                                                    Department of Pediatric Surgery,\r\n                                                                                    Hyogo Prefectural Kobe Children's\r\n                                                                                    Hospital)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                            <li>\r\n                                                                                <span class=\"-head\">2.<\/span>\r\n                                                                                <span class=\"-body\">Treatment of\r\n                                                                                    intractable diseases: Current status\r\n                                                                                    and future of transplantation<br>\r\n                                                                                    Dr. Mikiko Ueda (Lecturer,\r\n                                                                                    Department of Transplantation\r\n                                                                                    Surgery, Faculty of Medicine, Kyoto\r\n                                                                                    Univ.)\r\n                                                                                <\/span>\r\n                                                                            <\/li>\r\n                                                                        <\/ul>\r\n                                                                    <\/span>\r\n                                                                <\/li>\r\n                                                            <\/ul>\r\n                                                        <\/td>\r\n\r\n                                                    <\/tr>\r\n                                                <\/table>\r\n                                            <\/div>\r\n                                            -->\r\n\r\n\r\n                                        <\/div>\r\n                                    <\/div>\r\n\r\n\r\n                                    <ul class=\"c-flex -center -spB c-btnWrap--col2\">\r\n                                        <li>\r\n                                            <a href=\"#_js\" data-target_tab_btn=\"tab_target2\"\r\n                                                class=\"c-btn noScroll js-tabTrigger-otherBtn\">Product List<\/a>\r\n                                        <\/li>\r\n                                        <li>\r\n                                            <a href=\"\/en\/field\/\" class=\"c-btn\">The Business Fields<\/a>\r\n                                        <\/li>\r\n                                    <\/ul>\r\n\r\n                                <\/section>\r\n                                <section class=\"c-tabTarget_content tab_target2 isOn-\">\r\n                                    <div class=\"inner\">\r\n                                        <ul class=\"c-flex -spB c-listNav_anchor\">\r\n                                            <li>\r\n                                                <a href=\"#anchor3\" class=\"c-btn -arrow_bottom\">UBASTEC-AUTO<\/a>\r\n                                            <\/li>\r\n                                            <li>\r\n                                                <a href=\"#anchor4\" class=\"c-btn -arrow_bottom\">ARABINITEC-AUTO<\/a>\r\n                                            <\/li>\r\n                                        <\/ul>\r\n\r\n                                        <div class=\"c-section pdt0 c-beforeBgColor-\">\r\n\r\n                                            <div class=\"p-itemWrap\">\r\n                                                <ul class=\"c-block c-flex c-col2 mgt0\" id=\"anchor3\">\r\n                                                    <li>\r\n                                                        <h2 class=\"c-title -small -left\">\r\n                                                            <span class=\"head\">UBASTEC-AUTO<\/span>\r\n                                                        <\/h2>\r\n                                                    <\/li>\r\n                                                    <li>\r\n                                                        <p class=\"c-text\">In-vitro diagnostics<br>\r\n                                                            Reagent for determination of urinary bile acid sulfate (for\r\n                                                            automatic analyzers)<br>\r\n                                                            Certification Number: 222AHAMX00022000<\/p>\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n                                                <ul class=\"c-block c-flex c-col2 -reverse\">\r\n                                                    <li>\r\n                                                        <p class=\"c-text c-bold\"><!-- Measurement of urinary sulfated bile acid is -->\r\n                                                            A revolutionary test method that allows liver\r\n                                                            function testing without blood sampling.\r\n                                                        <\/p>\r\n\r\n                                                        <!-- \r\n                                                        <div class=\"c-text\">\r\n                                                            <h3 class=\"c-title5\">High Specificity Toward Hepatobiliary\r\n                                                                Diseases<\/h3>\r\n                                                            The concentration of urinary bile acid sulfate elevates\r\n                                                            specifically in hepatobiliary diseases.\r\n                                                            Especially, cholestasis and severe liver diseases indicate\r\n                                                            high value of urinary bile acid sulfate.\r\n                                                        <\/div>\r\n                                                        <div class=\"c-text\">\r\n                                                            <h3 class=\"c-title5\">Screening for Congenital Biliary\r\n                                                                Atresia<\/h3>\r\n                                                            Urinary sulfated bile acid (USBA) is useful for screening of\r\n                                                            neonatal and infantile jaundice, especially congenital\r\n                                                            biliary atresia.\r\n                                                        <\/div>\r\n                                                        <div class=\"c-text\">\r\n                                                            <h3 class=\"c-title5\">Extremely High Abnormal Detection Rate\r\n                                                                in Urine Tests<\/h3>\r\n                                                            Compared to the urine urobilinogen test strip method,\r\n                                                            urinary sulfated bile acid (USBA) has dramatically improved\r\n                                                            the abnormal detection rate.\r\n                                                        <\/div>\r\n                                                        -->\r\n\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n\r\n                                                <!-- \r\n                                                <div class=\"c-block2\">\r\n                                                    <h3 class=\"c-title2\">Clinical Case<\/h3>\r\n                                                    <p class=\"c-text\">UBAS levels in various hepatobiliary\r\n                                                        diseases<sup>*1<\/sup><\/p>\r\n                                                    <ul class=\"c-block2 c-flex -center c-col\">\r\n                                                        <li>\r\n                                                            <div class=\"pic\"><img decoding=\"async\"\r\n                                                                    src=\"\/assets\/img\/field\/diagnostics\/ub_pic01_en.png\"\r\n                                                                    alt=\"\"><\/div>\r\n                                                        <\/li>\r\n                                                    <\/ul>\r\n                                                <\/div>\r\n                                                -->\r\n\r\n                                                <div class=\"c-block2\">\r\n                                                    <h3 class=\"c-title2\">Assay Principal<\/h3>\r\n                                                    <!-- <p class=\"c-text\"><\/p> -->\r\n                                                    <div class=\"inner -middle\">\r\n                                                        <ul class=\"c-block2- c-flex -center c-col p-element01-\">\r\n                                                            <li>\r\n                                                                <div class=\"pic c-bgColor--white\"><img decoding=\"async\"\r\n                                                                        src=\"\/assets\/img\/field\/diagnostics\/ub_pic02_en.png\"\r\n                                                                        alt=\"\"><\/div>\r\n                                                            <\/li>\r\n                                                        <\/ul>\r\n                                                    <\/div>\r\n                                                <\/div>\r\n\r\n                                                <!-- \r\n                                                <div class=\"c-block2\">\r\n                                                    <h3 class=\"c-title2\">Features<\/h3>\r\n                                                    <p class=\"c-text\"><\/p>\r\n                                                    <ul class=\"c-indent\">\r\n                                                        <li><span class=\"-head\">\u25cf<\/span><span class=\"-body\">Self-sample\r\n                                                                blank method enables measurement on a single\r\n                                                                channel.<\/span><\/li>\r\n                                                        <li><span class=\"-head\">\u25cf<\/span><span class=\"-body\">No sample\r\n                                                                pretreatment is required, and urinary sulfate-conjugated\r\n                                                                bile acids can be measured in a short time.<\/span>\r\n                                                        <\/li>\r\n                                                        <li><span class=\"-head\">\u25cf<\/span><span class=\"-body\">High\r\n                                                                sensitivity and excellent reproducibility.<\/span><\/li>\r\n                                                        <li><span class=\"-head\">\u25cf<\/span><span class=\"-body\">Excellent\r\n                                                                stability after reagent preparation.<\/span><\/li>\r\n                                                        <li><span class=\"-head\">\u25cf<\/span><span class=\"-body\">Using a\r\n                                                                chromogenic agent that produces water-soluble formazan,\r\n                                                                which does not contaminate the cell of an automated\r\n                                                                analyzer.<\/span>\r\n                                                        <\/li>\r\n                                                        <li><span class=\"-head\">\u25cf<\/span><span class=\"-body\">Applicable\r\n                                                                to various types of automatic analyzers.<\/span><\/li>\r\n                                                    <\/ul>\r\n                                                <\/div>\r\n                                                -->\r\n\r\n                                                <div class=\"c-block2\">\r\n                                                    <h3 class=\"c-title5\">Package <!-- and Method of Storage --><\/h3>\r\n                                                    <div class=\"c-tableWrapSp js-scrollWrap\">\r\n                                                        <div class=\"c-figScroll\"><img decoding=\"async\"\r\n                                                                src=\"\/assets\/img\/fig_scroll_en.png\" alt=\"\"><\/div>\r\n                                                        <table class=\"c-table p-table02\">\r\n                                                            <tr>\r\n                                                                <th class=\"-col1 -border-left0\">Name<\/th>\r\n                                                                <th class=\"-col2\" colspan=\"2\">Constituent reagent<\/th>\r\n                                                                <th class=\"-col3 -border-right0\" colspan=\"2\">Package\r\n                                                                <\/th>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col1 -border-left0\" rowspan=\"5\">UBASTEC-AUTO\r\n                                                                <\/td>\r\n                                                                <td class=\"-col4\" rowspan=\"2\">Reagent 1<\/td>\r\n                                                                <td class=\"-col5\">Enzyme<\/td>\r\n                                                                <td class=\"-col6\">For 11 ml-solvent<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d72<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col5\">Solvent<\/td>\r\n                                                                <td class=\"-col6\">11 ml<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d72<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col4\" rowspan=\"2\">Reagent 2<\/td>\r\n                                                                <td class=\"-col5\">Enzyme<\/td>\r\n                                                                <td class=\"-col6\">For 5 ml-solvent<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d72<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col5\">Solvent<\/td>\r\n                                                                <td class=\"-col6\">5 ml<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d72<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col8\" colspan=\"2\">Standard solution<\/td>\r\n                                                                <td class=\"-col6\">10 ml<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d71<\/td>\r\n                                                            <\/tr>\r\n                                                        <\/table>\r\n                                                    <\/div>\r\n                                                <\/div>\r\n\r\n                                                <div class=\"c-block2\">\r\n                                                    <p class=\"c-head\">References<\/p>\r\n                                                    <ul class=\"c-indent c-caption mgt0\">\r\n                                                        <li><span class=\"-head\">*1&nbsp;<\/span><span\r\n                                                                class=\"-body\">Uenoyama R., Baba S., et al : KAN.TAN.SUI\r\n                                                                (Japanese), 31, 315-326 (1995)<\/span><\/li>\r\n                                                        <li><span class=\"-head\">*2&nbsp;<\/span><span class=\"-body\">Meng\r\n                                                                G., Mashige F., Kitamura K., et al : Jpn. J. Clin.\r\n                                                                Chem., 23, 150-157 (1994)<\/span><\/li>\r\n                                                        <li><span class=\"-head\">*3&nbsp;<\/span><span\r\n                                                                class=\"-body\">Adachi K., Kakigawa K., et al : Jpn. J.\r\n                                                                Clin. Chem., 26, 95-100 (1998)<\/span><\/li>\r\n\r\n                                                        <!-- \r\n                                                        <li><span class=\"-head\">*4&nbsp;<\/span><span\r\n                                                                class=\"-body\">Matsui A., et al., The Journal of\r\n                                                                Pediatrics, 129, 306 (1996)<\/span><\/li>\r\n                                                        <li><span class=\"-head\">*5&nbsp;<\/span><span\r\n                                                                class=\"-body\">Tazuke Y., Kodama N., Adachi K., et al :\r\n                                                                Jpn. J. Clin. Chem., 21, 249-258 (1992)<\/span><\/li>\r\n                                                        -->\r\n\r\n                                                    <\/ul>\r\n                                                <\/div>\r\n\r\n                                                <div class=\"c-block2\">\r\n                                                    <p class=\"c-text mgt0\">\r\n                                                        Distributed by \r\n                                                        <a href=\"https:\/\/azscience.jp\/en\/\" rel=\"noopener\" target=\"_blank\">\r\n                                                            AZ Science Co., Ltd.\r\n                      <!--\r\n                      This SVG uses some of the following library:\r\n                      Font Awesome Free 5.13.0 by @fontawesome - https:\/\/fontawesome.com\r\n                      License - https:\/\/fontawesome.com\/license\/free (Icons: CC BY 4.0, Fonts: SIL OFL 1.1, Code: MIT License)\r\n                      -->\r\n                      <svg class=\"svg icon\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" width=\"15\" height=\"15\" viewBox=\"0 0 12 12\">\r\n                        <defs>\r\n                          <style>\r\n                            .cls-1 {\r\n                              fill: #333;\r\n                              fill-rule: evenodd;\r\n                            }\r\n                          <\/style>\r\n                        <\/defs>\r\n                        <path id=\"\" data-name=\"\" class=\"cls-1\" d=\"M7595.84,1210.9h-0.75a0.38,0.38,0,0,0-.38.38v2.62h-7.5v-7.5h3.38a0.376,0.376,0,0,0,.37-0.37v-0.75a0.378,0.378,0,0,0-.37-0.38h-3.75a1.135,1.135,0,0,0-1.13,1.13v8.25a1.127,1.127,0,0,0,1.13,1.12h8.25a1.118,1.118,0,0,0,1.12-1.12v-3A0.378,0.378,0,0,0,7595.84,1210.9Zm1.31-7.5h-3a0.565,0.565,0,0,0-.4.96l0.84,0.84-5.71,5.71a0.556,0.556,0,0,0,0,.8l0.53,0.53a0.568,0.568,0,0,0,.79,0l5.71-5.71,0.84,0.83a0.56,0.56,0,0,0,.96-0.39v-3A0.561,0.561,0,0,0,7597.15,1203.4Z\" transform=\"translate(-7585.72 -1203.41)\"\/>\r\n                      <\/svg>\r\n                                                        <\/a>\r\n                                                    <\/p>\r\n                                                <\/div>\r\n\r\n                                                <!-- \r\n                                                <ul class=\"c-block c-flex c-col\">\r\n                                                    <li>\r\n                                                        <h3 class=\"c-title3\">Urinary Sulfated Bile Acid (USBA)<\/h3>\r\n                                                        <p class=\"c-text\">\r\n                                                            Urinary sulfated bile acid (USBA) is an ester consists of\r\n                                                            bile acid and sulfate. The most common type of USBA in vivo\r\n                                                            is the one with ester bond on the 3-hydroxyl group of bile\r\n                                                            acid. Sulfate conjugation of bile acid occurs mainly in the\r\n                                                            liver and is catalyzed by bile salt sulfotransferase (EC\r\n                                                            2.8.2.14) in the soluble fraction of hepatocytes. The\r\n                                                            conjugation increases its polarity and renal clearance by\r\n                                                            several- to several hundred-fold. Thus it is considered as a\r\n                                                            detoxification mechanism for the rapid excretion of excess\r\n                                                            bile acid from the body when blood bile acid levels increase\r\n                                                            due to abnormalities in the hepatobiliary system.<br>\r\n                                                            The daily USBA excretion in healthy adult is very small,\r\n                                                            ranging from 1 to 7 \u03bcmol. But when blood bile acids increase\r\n                                                            due to abnormalities in the hepatobiliary system, urinary\r\n                                                            bile acids increase accordingly. USBA is the most abundant\r\n                                                            component of urinary bile acids, which often accounts for\r\n                                                            more than 50% of the total. Therefore, when measuring\r\n                                                            urinary bile acids, it is important to measure sulfated bile\r\n                                                            acid, as large amount of sulfated bile acid are excreted in\r\n                                                            the urine of patients with hepatobiliary diseases.\r\n                                                        <\/p>\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n                                                -->\r\n\r\n                                            <\/div>\r\n\r\n\r\n                                        <\/div>\r\n                                    <\/div>\r\n\r\n                                    <div class=\"c-section c-beforeBgColor -bgBlue\">\r\n                                        <div class=\"inner\">\r\n                                            <div class=\"p-itemWrap\">\r\n\r\n                                                <ul class=\"c-block c-flex c-col2 mgt0\" id=\"anchor4\">\r\n                                                    <li>\r\n                                                        <h2 class=\"c-title -small -left\">\r\n                                                            <span class=\"head\">ARABINITEC-AUTO<\/span>\r\n                                                        <\/h2>\r\n                                                    <\/li>\r\n                                                    <li>\r\n                                                        <!-- <h3 class=\"c-title2\"><\/h3> -->\r\n                                                        <p class=\"c-text\">\r\n                                                           Reagent for determination of D-arabinitol in serum (for automatic analyzer)\r\n                                                        <\/p>\r\n                                                    <\/li>\r\n                                                <\/ul>\r\n\r\n                                                <div class=\"c-block2\">\r\n                                                    <h3 class=\"c-title2\">Assay Principal<\/h3>\r\n                                                    <!-- <p class=\"c-text\"><\/p> -->\r\n                                                    <div class=\"inner -middle\">\r\n                                                        <ul class=\"c-block2- c-flex -center c-col p-element01-\">\r\n                                                            <li>\r\n                                                                <div class=\"pic c-bgColor--white\"><img decoding=\"async\"\r\n                                                                        src=\"\/cms\/wp-content\/uploads\/2024\/09\/arabinitec-en.png\"\r\n                                                                        alt=\"\"><\/div>\r\n                                                            <\/li>\r\n                                                        <\/ul>\r\n                                                    <\/div>\r\n                                                <\/div>\r\n\r\n                                                <div class=\"c-block2\">\r\n                                                    <h3 class=\"c-title5\">Package<\/h3>\r\n                                                    <div class=\"c-tableWrapSp js-scrollWrap\">\r\n                                                        <div class=\"c-figScroll\"><img decoding=\"async\" src=\"\/assets\/img\/fig_scroll.png\"\r\n                                                                alt=\"\"><\/div>\r\n                                                        <table class=\"c-table p-table02\">\r\n                                                            <tr>\r\n                                                                <th class=\"-col1 -border-left0\">Name<\/th>\r\n                                                                <th class=\"-col2\" colspan=\"2\">Constituent reagent<\/th>\r\n                                                                <th class=\"-col3 -border-right0\" colspan=\"2\">Package<\/th>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col1 -border-left0\" rowspan=\"7\">ARABINITEC-AUTO\r\n                                                                <\/td>\r\n                                                                <td class=\"-col4\" rowspan=\"2\">Reagent 1<\/td>\r\n                                                                <td class=\"-col5\">Enzyme<\/td>\r\n                                                                <td class=\"-col6\">For 16 ml-solvent<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d74<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col5\">Solvent<\/td>\r\n                                                                <td class=\"-col6\">16 ml<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d74<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col4\" rowspan=\"2\">Reagent 2<\/td>\r\n                                                                <td class=\"-col5\">Enzyme<\/td>\r\n                                                                <td class=\"-col6\">For 5 ml-solvent<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d74<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col5\">Solvent<\/td>\r\n                                                                <td class=\"-col6\">5 ml<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d74<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col4\" rowspan=\"3\">Standard solution<\/td>\r\n                                                                <td class=\"-col5\">20 \u03bcM<\/td>\r\n                                                                <td class=\"-col6\">10 ml<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d71<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col5\">100 \u03bcM<\/td>\r\n                                                                <td class=\"-col6\">10 ml<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d71<\/td>\r\n                                                            <\/tr>\r\n                                                            <tr>\r\n                                                                <td class=\"-col5\">1,000 \u03bcM<\/td>\r\n                                                                <td class=\"-col6\">10 ml<\/td>\r\n                                                                <td class=\"-col7 -border-right0\">\u00d71<\/td>\r\n                                                            <\/tr>\r\n                                                        <\/table>\r\n                                                    <\/div>\r\n                                                <\/div>\r\n\r\n                                            <\/div>\r\n                                        <\/div>\r\n                                    <\/div>\r\n\r\n\r\n\r\n                                    <ul class=\"c-flex -center -spB c-btnWrap--col2\">\r\n                                        <li>\r\n                                            <a href=\"#_js\" data-target_tab_btn=\"tab_target1\"\r\n                                                class=\"c-btn noScroll js-tabTrigger-otherBtn\">Business and\r\n                                                Technology<\/a>\r\n                                        <\/li>\r\n                                        <li>\r\n                                            <a href=\"\/en\/field\/\" class=\"c-btn\">The Business Fields<\/a>\r\n                                        <\/li>\r\n                                    <\/ul>\r\n                                <\/section>\r\n                            <\/div>\r\n                        <\/div>\r\n                    <\/div>\r\n                <\/div>\r\n\r\n            <\/main>\r\n","protected":false},"excerpt":{"rendered":"<p>HOME The Business Fields Diagnostics Diagnostics Making full use of our proprietary biotechnology we have cult 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